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hiv susceptibility

Study: Why Whites Are Less Susceptible to AIDS: The Burger team focused on a genetic mutation that had previously been shown in men to be protective against HIV infection. The mutant gene, called delta-32, if inherited from both parents, results in an abnormal, and in this case protective, receptor called ccR5 on the surface of their cells. [...] Overall, the researchers discovered that all HIV-negative women were about twice as likely to have the protective delta-32 gene than were infected women. [...] White women carry the heterozygous form of delta-32 far more frequently than any other women. About 1.2 percent of all white women who are HIV-negative carry the mutant gene. Only 0.6 percent of the HIV-infected white women carry the gene. Only 0.2 percent of HIV-negative African-American women carry the delta-32 gene. And among those who are HIV-positive, the frequency of delta- 32 is only 0.1 percent, or half as much.

So effectively, chances of getting HIV are at least partially both race-linked and sex-linked genetically.

Good grief.

I suppose that it does, in part, explain why the great Heterosexual AIDS Epidemic didn't happen in caucasians here, and did happen in blacks.

Posted by iain at March 01, 2002 10:09 AM

 

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