Study: Why Whites Are Less Susceptible to AIDS: The Burger team focused on a genetic mutation that had previously been shown in men to be protective against HIV infection. The mutant gene, called delta-32, if inherited from both parents, results in an abnormal, and in this case protective, receptor called ccR5 on the surface of their cells. [...] Overall, the researchers discovered that all HIV-negative women were about twice as likely to have the protective delta-32 gene than were infected women. [...] White women carry the heterozygous form of delta-32 far more frequently than any other women. About 1.2 percent of all white women who are HIV-negative carry the mutant gene. Only 0.6 percent of the HIV-infected white women carry the gene. Only 0.2 percent of HIV-negative African-American women carry the delta-32 gene. And among those who are HIV-positive, the frequency of delta- 32 is only 0.1 percent, or half as much.
So effectively, chances of getting HIV are at least partially both race-linked and sex-linked genetically.
I suppose that it does, in part, explain why the great Heterosexual AIDS Epidemic didn't happen in caucasians here, and did happen in blacks.Posted by iain at March 01, 2002 10:09 AM